Small nerve fibres are also present in the cornea of the eye. The cornea confocal microscope consists of a microscope and a special camera, suitable for taking pictures of the cornea. It is then possible to examine the small nerve fibre density.
Before the pictures are taken, the eye is anesthetised with eye drops. Also a gel is applied, followed by placing the lens of the microscope. The gel forms a barrier between the eye and the lens; therefore, there is no direct contact of the lens with the eye. Taking pictures takes only a few minutes.

Besides skin biopsy and temperature threshold testing, cornea confocal microscopy seems a valuable diagnostic tool for the diagnosis of small fibre neuropathy.

More information can be found in the brochure brochure over de cornea confocal microscopy (in Dutch).